MRCOG1 Free MCQS 2

Question 7: Normal pregnancy is associated with
T Decreased protein S concentration
F Increased fibrinolysis
T Increased plasminogen activator inhibitor concentration
F A fall in the concentration of fibrin degradation products
Question 8: With respect to the rennin-angiotensin pathway in pregnancy
T Plasma renin concentration is increased in pregnancy
T Plasma renin activity is increased in pregnancy
F Plasma angiotensinogen concentration falls during pregnancy
F Rennin readily crosses the placenta
Question 9: During pregnancy
F Arterial PO2 is increased
F Residual volume is increased
F Physiological dead space is decreased
F Vital capacity is increased
Question 10: The following changes occur in the cardiovascular system
during pregnancy
T Increased heart rate by 20 weeks gestation
F Decreased stroke volume
F Increased pulmonary capillary pressure in the third trimester
T Decreased peripheral vascular resistance
Question 11: During pregnancy
F Expiratory reserve is increased
T The respiratory quotient is increased
T The sub-costal angle is increased
F Peak expiratory flow rate is decreased
Question 12: During pregnancy
T The forced expiratory volume in one second is unchanged
F Arterial bicarbonate concentration is increased
F There is a respiratory alkalosis
T There is a fall in arterial PCO2
Question 13: The following changes occur in the fetal circulation at birth
T Closure of the umbilical arteries
Closure of the umbilical vein
Closure of the ductus venosus
Closure of the ductus arteriosus


Question 14: Normal pregnancy is associated with
F A decrease in urinary erythropoietin excretion
T An increase in mean cell volume of erythrocytes
F An increase in platelet count
F A decrease in leucocyte count
Question 15: The following changes occur in the cardiovascular system
during pregnancy
T Increased myocardial contractility
F Increase in the arterio-venous oxygen difference
T Increased oxygen carrying capacity of blood
T Decreased haemoglobin concentration

Respiratory physiology MCQ

Question 1: With respect to inspired, expired and alveolar air
F Expired air contains 5% oxygen
T Alveolar air contains 5% CO2
F Alveolar air contains 30% oxygen
T Alveolar air contains 75% nitrogen
Question 2: The following factors affect the rate of gas diffusion through the
respiratory membrane
T Thickness of the respiratory membrane
T Surface area of the membrane
T Diffusion coefficient of the gas
T Partial pressure difference between the two sides of the membrane
Question 3: With respect to the binding of carbon monoxide to haemoglobin
F The binding site of carbon monoxide to Hb is different from that of oxygen
T Haemoglobin has a higher affinity for carbon monoxide than for oxygen
F 97% of carbon monoxide transported by blood is in solution in the water of plasma
T The carbon monoxide – Hb dissociation curve lies to the left of the oxygen
– Hb dissociation curve
Question 4: With respect to gas exchange across the alveolar membrane
F The partial pressure of oxygen in alveolar air is 104mmHg
T The partial pressure of oxygen in deoxygenated alveolar blood is 40mmHg
T The partial pressure of oxygenated blood leaving the alveoli is 104mmHg
F The partial pressure of oxygen in blood leaving the left ventricle is
104mmHg
Question 5: Surfactant
T Is a lipoprotein
F Is secreted by type I pneumocytes
FIncreases the surface tension of the alveolar fluid
T May be deficient in premature babies
Question 6: Carbon dioxide is transported in blood in the following forms
T In solution in the water of plasma
T As bicarbonate ion
F Combined to haemoglobin to form carboxy-haemoglobin
T Bound to plasma proteins
Question 7: During the release of carbon dioxide in the lungs
T The binding of oxygen to haemoglobin displaces carbon dioxide from blood
T The binding of oxygen to haemoglobin causes the release of hydrogen ions
T Hydrogen ions combine with bicarbonate to form carbonic acid
T Carbonic acid dissociated into carbon dioxide and water
Question 8: With respect to gas exchange across the alveolar membrane
F The oxygen saturation in venous blood is 40%
T On average, the haemoglobin in 100ml of blood can combine with 20ml of
oxygen
F Acidosis causes the oxygen – Hb dissociation curve to shift to the left
T Increased CO2 concentration causes the oxygen – Hb dissociation curve to
shift to the right
Question 9: Minute respiratory volume
F Is about 60l/min
T Increases in pregnancy
T Is tidal volume X respiratory rate
T Is the total volume of new air moved into the respiratory tract each minute
Question 10: With respect to gas exchange across the alveolar membrane
F Oxygen diffusion across the alveolar membrane is more rapid than carbon
dioxide diffusion
F The intracellular partial pressure of CO2 is 100mmHg
T The partial pressure of CO2 in tissue fluid is 45mmHg
F The partial pressure of CO2 in venous blood leaving tissues is 40mmHg
Question 11: Carbonic anhydrase
F Is present in plasma
T Is present in erythrocytes
F Catalyses the reaction between carbon dioxide and haemoglobin
F Catalyses the decomposition of carbonic acid into bicarbonate and
hydrogen ions
Question 12: The following are recognised causes of bronchoconstriction
T Histamine
T Prostaglandins
F Vasopressin
F Noradrenaline
Question 13: With respect to gas exchange across the alveolar membrane|
F Pyrexia causes the oxygen – Hb dissociation curve to shift to the left
T An increase in the concentration of 2,3-diphosphoglycerate causes the
oxygen – Hb dissociation curve to shift to the right
True False
b.
Hadidy's answer: No answer Correct answer: true
F FFFFF The oxygen – Hb dissociation curve of fetal Hb lies to the right of that of
adult Hb
FFFF Exercise shifts the oxygen – Hb dissociation curve to the left
Question 14: Peripheral chemoreceptors
F Are located in the carotid sinus
T Are located in the aortic body
T Are more sensitive to changes in PO2 than the central chemoreceptors
T Have a rich blood supply
Question 15: Vital capacity
F Is increased in the third trimester of pregnancy
T Is dependent on the compliance of the lungs and chest wall
T Is dependent on the strength of the respiratory muscle
F Is higher in obese individuals compared to tall thin individuals